Cancer-Predisposing Gene
Definition of Cancer-Predisposing Gene:
Mutated forms of genes which encode proteins that are essential for the control and maintenance of normal cellular processes. Inherited or somatic mutations in the wild-type form of these genes alters control of their expression, resulting in a change in control of the cell cycle. Individuals who harbor cancer-predisposing genes require fewer somatic mutations for transformation of a particular cell, thereby predisposing them to the development of cancer.
Cancer-Predisposing Gene is part of the Susceptibility-Resistance Gene group
Cancer-Predisposing Gene is also know as:
Cancer Susceptibility Gene
Susceptibility Gene